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Disease	Synonyms	Description	Articles
Legius syndrome	LGSS; neurofibromatosis type 1-like syndrome; NF1-.. [+] LGSS; neurofibromatosis type 1-like syndrome; NF1-like syndrome [-]	A RASopathy characterized by multiple cafe-au-lait..[+] A RASopathy characterized by multiple cafe-au-lait macules and possible skin fold freckling without neurofibromas, optic gliomas, or Lisch nodules that has_material_basis_in heterozygous mutation in the SPRED1 gene on chromosome 15q14. [-]
lymphoblastic lymphoma		A lymphoma that has_material_basis_in immature mal..[+] A lymphoma that has_material_basis_in immature malignant lymphocytes (lymphoblasts) committed to the B-cell or T-cell lineage and located_in primarily lymph nodes or located_in extranodal sites. [-]
lupus nephritis		A glomerulonephritis that is characterized by infl..[+] A glomerulonephritis that is characterized by inflammation of the kidneys resulting from systemic lupus erythematosus. [-]
lysosomal acid lipase deficiency		A lipid storage disease characterized by lysosomal..[+] A lipid storage disease characterized by lysosomal and lipase deficiency. [-]
leukocyte adhesion deficiency 2		A leukocyte adhesion deficiency that is characteri..[+] A leukocyte adhesion deficiency that is characterized by the absence of Sialyl Lewis X of E-selectin resulting in recurrent bacterial infections, severe growth delay and severe intellectual deficit. [-]
Larsen-like syndrome B3GAT3 type	Larsen-like syndrome, B3GAT3 type; multiple joint .. [+] Larsen-like syndrome, B3GAT3 type; multiple joint dislocations-short stature-craniofacial dysmorphism-congenital heart defects syndrome [-]	A syndrome that is characterized by laxity, disloc..[+] A syndrome that is characterized by laxity, dislocations and contractures of the joints, short stature, foot deformities (e.g. clubfeet), broad tips of fingers and toes, short neck, dysmorphic facial features (hypertelorism, downslanting palpebral fissures, upturned nose with anteverted nares, high arched palate) and various cardiac malformations and has_material_basis_in homozygous mutation in the B3GAT3 gene on chromosome 11q12. [-]
lymph node benign neoplasm		An immune system organ benign neoplasm that is loc..[+] An immune system organ benign neoplasm that is located_in the lymph nodes. [-]
lymph node carcinoma		A lymph node cancer that has_material_basis_in abn..[+] A lymph node cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. [-]
luminal breast carcinoma B	Luminal B Breast Carcinoma	A breast carcinoma that is characterized by low to..[+] A breast carcinoma that is characterized by low to moderate expression of genes characteristic of luminal epithelial cells including estrogen receptor (ER), and high expression of GGH, LAPTM4B, and CCNE1. [-]
Libman-Sacks endocarditis	Libmann–Sachs, Endocarditis in systemic lupus eryt.. [+] Libmann–Sachs, Endocarditis in systemic lupus erythematosus [-]	An endocarditis that is characterized by Libman-Sa..[+] An endocarditis that is characterized by Libman-Sacks vegetations, is common in patients with systemic lupus erythematosus and is commonly complicated with embolic cerebrovascular disease. [-]
limbic encephalitis		An encephalitis that is characterized by subacute ..[+] An encephalitis that is characterized by subacute onset of short-term memory deficits, seizures or psychiatric symptoms located_in the medial temporal lobes. [-]
laryngomalacia	congenital laryngomalacia	A laryngeal disease that is characterized by inwar..[+] A laryngeal disease that is characterized by inward collapse of flaccid supraglottic structures during inspiration. The most common symptom is noisy breathing (stridor) that is often worse when the infant is on his/her back or crying. [-]
latent autoimmune diabetes in adults	LADA; type 1.5 diabetes	A type 1 diabetes mellitus that is characterized b..[+] A type 1 diabetes mellitus that is characterized by a less intensive autoimmune process, highly variable β-cell destruction, different degrees of insulin resistance and heterogeneous titre and pattern of islet autoantibody, sharing features with both type 1 and type 2 diabetes mellitus. [-]
long COVID	chronic COVID-19; post-COVID syndrome; PASC; post-.. [+] chronic COVID-19; post-COVID syndrome; PASC; post-acute sequelae of SARS-CoV-2 infection [-]	A Coronavirus infectious disease that is character..[+] A Coronavirus infectious disease that is characterized by long-term persistent and fluctuating symptoms, in individuals with COVID-19, persisting beyond three to four weeks, including the loss of the ability to smell and taste, breathlessness, fatigue, difficulty in breathing, difficulty concentrating, memory loss, confusion, headache, heart palpitations, chest pain, pain with deep breaths, dizziness, and tachycardia. [-]
Leber congenital amaurosis 19		A Leber congenital amaurosis that has_material_bas..[+] A Leber congenital amaurosis that has_material_basis_in mutation in the USP45 gene on chromosome 6q16. [-]
lymphomatoid granulomatosis		A lymphoproliferative syndrome that is characteriz..[+] A lymphoproliferative syndrome that is characterized by overproduction (proliferation) of white blood cells called lymphocytes. The abnormal cells infiltrate and accumulate (form lesions or nodules) within tissues. The lesions or nodules damage or destroy the blood vessels within these tissues. [-]
LADD syndrome	lacrimoauriculodentodigital syndrome; Lacrimo-auri.. [+] lacrimoauriculodentodigital syndrome; Lacrimo-auriculo-dento-digital (LADD) syndrome [-]	A syndrome that is characterized by defects in the..[+] A syndrome that is characterized by defects in the tear-producing lacrimal system, ear problems, dental abnormalities, and deformities of the fingers. [-]
lacrimoauriculodentodigital syndrome 2	Lacrimo-auriculo-dento-digital syndrome 2	A LADD syndrome that has_material_basis_in heteroz..[+] A LADD syndrome that has_material_basis_in heterozygous mutation in the tyrosine kinase domain of the FGFR3 gene on chromosome 4p16 and that is mainly affecting lacrimal glands and ducts, salivary glands and ducts, ears, teeth, and distal limb segments. [-]
lacrimoauriculodentodigital syndrome 3	Lacrimo-auriculo-dento-digital syndrome 3	A LADD syndrome that is characterized by aplasia, ..[+] A LADD syndrome that is characterized by aplasia, atresia or hypoplasia of the lacrimal and salivary systems, cup-shaped ears, hearing loss, and dental and digital anomalies and that has_material_basis_in heterozygous mutation in the FGF10 gene on chromosome 5p12. [-]
logopenic progressive aphasia	logopenic variant PPA; Logopenic primary progressi.. [+] logopenic variant PPA; Logopenic primary progressive aphasia [-]	A primary progressive aphasia that is characterize..[+] A primary progressive aphasia that is characterized by language disturbance, including difficulty making or understanding speech. It is a type of primary progressive aphasia. Affected individuals have slow, hesitant speech due to difficulty retrieving the correct words, names, or numbers. [-]
lethal congenital glycogen storage disease of heart	fatal congenital nonlysosomal cardiac glycogenosis.. [+] fatal congenital nonlysosomal cardiac glycogenosis; fatal congenital hypertrophic cardiomyopathy due to glycogenosis; fatal congenital hypertrophic cardiomyopathy due to GSD; phosphorylase kinase deficiency of heart; fatal congenital nonlysosomal cardiac glycogenosis [-]	A glycogen storage disease characterized by glycog..[+] A glycogen storage disease characterized by glycogenosis confined to the heart, hypoglycemia and cyanosis, and has_material_basis_in autosomal dominant inheritance of heterozygous mutation in the gene encoding the noncatalytic gamma-2 subunit of AMP-activated protein kinase (PRKAG2) on chromosome 7q36. [-]
Leber congenital amaurosis 9	LCA9	A Leber congenital amaurosis that has_material_bas..[+] A Leber congenital amaurosis that has_material_basis_in mutation in the NMNAT1 gene on chromosome 1p36. [-]
Leber congenital amaurosis 2	LCA2; amaurosis congenita of Leber II	A Leber congenital amaurosis that is characterized..[+] A Leber congenital amaurosis that is characterized by night blindness, some transient improvement in vision, and eventual progressive visual loss and has_material_basis_in mutation in the RPE65 gene on chromosome 1. [-]
Leber congenital amaurosis 1	LCA1; amaurosis congenita of Leber I	A Leber congenital amaurosis characterized by seve..[+] A Leber congenital amaurosis characterized by severe cone-rod dystrophy with photophobia, high hyperopia, and poor but stable vision with no visual improvement and that has_material_basis_in mutation in the GUCY2D gene on chromosome 17p13. [-]
Leber congenital amaurosis 8	LCA8	A Leber congenital amaurosis that is characterized..[+] A Leber congenital amaurosis that is characterized by night blindness and thick unlaminated retinas and has_material_basis_in mutation in the CRB1 gene on chromosome 1q31-q32. [-]
Leber congenital amaurosis 12	LCA12	A Leber congenital amaurosis that has_material_bas..[+] A Leber congenital amaurosis that has_material_basis_in mutation in the RD3 gene on chromosome 1q32. [-]
Leber congenital amaurosis 16	LCA16	A Leber congenital amaurosis that has_material_bas..[+] A Leber congenital amaurosis that has_material_basis_in mutation in the KCNJ13 gene on chromosome 2q37. [-]
Leber congenital amaurosis 14	LCA14	A Leber congenital amaurosis that has_material_bas..[+] A Leber congenital amaurosis that has_material_basis_in mutation in the LRAT gene on chromosome 4q31. [-]
Leber congenital amaurosis 15	LCA15	A Leber congenital amaurosis that has_material_bas..[+] A Leber congenital amaurosis that has_material_basis_in mutation in the TULP1 gene on chromosome 6p21.3. [-]
Leber congenital amaurosis 5	LCA5	A Leber congenital amaurosis that is characterized..[+] A Leber congenital amaurosis that is characterized by severe visual dysfunction, nystagmus, the oculodigital sign, and a normal fundus with onset in infancy and has_material_basis_in mutation in the LCA5 gene on chromosome 6q14.1. [-]
Leber congenital amaurosis 11	LCA11	A Leber congenital amaurosis that has_material_bas..[+] A Leber congenital amaurosis that has_material_basis_in mutation n the IMPDH1 gene on chromosome 7q31.3-q32. [-]
Leber congenital amaurosis 17	LCA17	A Leber congenital amaurosis that has_material_bas..[+] A Leber congenital amaurosis that has_material_basis_in mutation in the GDF6 gene on chromosome 8q22. [-]
Leber congenital amaurosis 10	LCA10	A Leber congenital amaurosis that is characterized..[+] A Leber congenital amaurosis that is characterized by severe infantile-onset cone-rod dystrophy with high hyperopia and severe ERG abnormalities and has_material_basis_in mutation in the CEP290 gene on chromosome 12q21.32. [-]
Leber congenital amaurosis 6	LCA6	A Leber congenital amaurosis that is characterized..[+] A Leber congenital amaurosis that is characterized by early photophobia, hypermetropia less than +7 diopters, and visual acuity in the range of 20/400 to count fingers and has_material_basis_in mutation in the RPGRIP1 gene on chromosome 14q11. [-]
Leber congenital amaurosis 13	LCA13	A Leber congenital amaurosis thatis characterized ..[+] A Leber congenital amaurosis thatis characterized by mild or absent hyperopia, transient improvement of visual acuity, and eventual macular atrophy with severe disease progression and has_material_basis_in mutation in the RDH12 gene on chromosome 14q23.3. [-]
Leber congenital amaurosis 3	LCA3	A Leber congenital amaurosis that has_material_bas..[+] A Leber congenital amaurosis that has_material_basis_in mutation in the SPATA7 gene on chromosome 14q31. [-]
Leber congenital amaurosis 4	LCA4	A Leber congenital amaurosis that is characterized..[+] A Leber congenital amaurosis that is characterized by a relatively severe phenotype, with maculopathy and marked bone-spicule pigmentary retinopathy in most and keratoconus and cataract in a large subset and that has_material_basis_in mutation in the AIPL1 gene on chromosome 17p13. [-]
Leber congenital amaurosis 7	LCA7	A Leber congenital amaurosis that has_material_bas..[+] A Leber congenital amaurosis that has_material_basis_in mutation in the CRX gene on chromosome 19q13. [-]
late-adult onset retinitis pigmentosa	senile retinitis pigmentosa	A retinitis pigmentosa that is characterized by on..[+] A retinitis pigmentosa that is characterized by onset of symptoms in the fifth or sixth decade of life. [-]
long QT syndrome 1	LQT1; ventricular fibrillation with prolonged QT i.. [+] LQT1; ventricular fibrillation with prolonged QT interval [-]	A long QT syndrome that has_material_basis_in domi..[+] A long QT syndrome that has_material_basis_in dominant inheritance of mutation in the KCNQ1 gene on chromosome 11p15.5-p15.4. [-]	8 articles
long QT syndrome 2	LQT2	A long QT syndrome that has_material_basis_in domi..[+] A long QT syndrome that has_material_basis_in dominant inheritance of mutation in the KCNH2 gene on chromosome 7q36.1. [-]	4 articles
long QT syndrome 3	LQT3	A long QT syndrome that has_material_basis_in domi..[+] A long QT syndrome that has_material_basis_in dominant inheritance of mutation in the SCN5A gene on chromosome 3p22.2. [-]	2 articles
long QT syndrome 5	LQT5	A long QT syndrome that has_material_basis_in domi..[+] A long QT syndrome that has_material_basis_in dominant inheritance of mutation in the KCNE1 gene on chromosome 21q22.12. [-]	2 articles
long QT syndrome 6	LQT6	A long QT interval syndrome that has_material_basi..[+] A long QT interval syndrome that has_material_basis_in dominant inheritance of mutation in the KCNE2 gene on chromosome 21q22.11. [-]
long QT syndrome 9	LQT9	A long QT syndrome that has_material_basis_in muta..[+] A long QT syndrome that has_material_basis_in mutation of the CAV3 gene on chromosome 3p25.3. [-]
long QT syndrome 10	LQT10	A long QT syndrome that has_material_basis_in domi..[+] A long QT syndrome that has_material_basis_in dominant inheritance of mutation in the SCN4B gene on chromosome 11q23.3. [-]
long QT syndrome 11	LQT11	A long QT syndrome that has_material_basis_in domi..[+] A long QT syndrome that has_material_basis_in dominant inheritance of mutation in the AKAP9 gene on chromosome 7q21.2. [-]
long QT syndrome 12	LQT12	A long QT syndrome that has_material_basis_in domi..[+] A long QT syndrome that has_material_basis_in dominant inheritance of mutation in the SNTA1 gene on chromosome 20q11.21. [-]
long QT syndrome 13	LQT13	A long QT syndrome that has_material_basis_in domi..[+] A long QT syndrome that has_material_basis_in dominant inheritance of mutation in the KCNJ5 gene on chromosome 11q24.3. [-]
long QT syndrome 14	LQT14	A long QT syndrome that has_material_basis_in domi..[+] A long QT syndrome that has_material_basis_in dominant inheritance of mutation in the CALM1 gene on chromosome 14q32.11. [-]

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